Meanwhile for modding/external programs to do OSR2/SR6 stuff there isn’t a general replacement to Intiface game wise (that I know of) as since these devices are so niche stuff need to be built to be highly customizable to enable someone to mod in support (Virt-a-mate is the only example I can think of although VaM has been a pain to set limits for me) or you need to make a specific alteration or make a program built with it in mind or directed at it. (Multifunplayer is the go to I think for video playing and this game mod which was done via funscript player)
I’ve not had my SR6 for even half a year yet so I’m not experienced at all with it compared to others here.