After some experimenting with the VERY rough input file - I can say that your upscale is very good. This is assuming you’re working from the same input file that @serialblue linked to. This is a video that is so artifact’ed and compressed that I probably wouldn’t have attempted it 
So even though the skin tones are pretty smeared, your result is good - given the input file.
I WOULD really suggest to only compress the file ONCE - at the very end. Make every effort to make your workflow lossless until the final step. The current version of Topaz is really terrible at this - they got rid of h.264 and we’re left with a bugged Prores HQ profile that outputs extremely bloated files. I personally run VEAI version 2.6.4 so I can do lossless h.264.
Also - for Flowframes, use RIFE 2.3. Subsequent models available in Flowframes trade quality for speed. I’m personally migrating to other apps that have the newest RIFE 4.6 model which handles 4k better. Flowframes has been abaonded a bit by the developer, so I’ve been playing with SVFI and enhancr with decent results.
Lastly, you can always check out my workflow at this post - https://discuss.eroscripts.com/t/what-is-g90ak-how-do-i-upscale-clean-videos/94275 I do find that my settings work best for “normal” quality videos and tend to stay away from low quality input - I may have to call that out along with my reccos.
Bravo - keep at it and don’t be afraid to ask questions.
I’ll update the thread with my attempt later today.