Some useful information discovered by @ZeroScripts :
TyranoBuilder can utilize “.tpatch” files to add additional data, or overwrite existing files, even if they’re still compiled in the .exe or app.asar. This allows us to include all the mod-specific content into a single file, which then can be easily added to the game.
The “.tpatch” file itself is simply made out of a .zip, containing all the necessary files in their original folder structure (e.g., [gamename]\tyrano\plugins\kag\kag.tag_ext.js), which is then changed to the extension .tpatch. The file must also have the same name as the game’s .exe and be in the same directory.